Molecular Formula | C9H9ClO2 |
Molar Mass | 184.62 |
Density | 1?+-.0.06 g/cm3(Predicted) |
Melting Point | 160 °C (decomp) |
Boling Point | 363.6±32.0 °C(Predicted) |
Appearance | Shape Solid, color Light Red to Pink |
pKa | 7.58±0.48(Predicted) |
Storage Condition | Refrigerator |
Physical and Chemical Properties | Crystallization of chemical properties. Melting point 155-164 ℃. |
Use | Use is an intermediate of salbutamol. |
Solubility | Acetonitrile (Slightly), DMSO (Sparingly), Methanol (Slightly) |
Preparation
It can be prepared by the reaction of 4-hydroxyacetophenone and zinc chloride under the action of formaldehyde and hydrochloric acid.
Production method
It is prepared with p-hydroxyacetophenone and chloromethylation of formaldehyde and concentrated hydrochloric acid.